Serie A leaders Inter are aiming to stretch their five-point lead over AS Roma when they visit bottom club Cagliari on Sunday night.
Despite a slew of injuries that would have hobbled a lesser squad, Inter will have centre-back Marco Materazzi back as they bid to reinforce media reports that new Cagliari coach Edo Sonetti, only appointed a month ago, could already be on his way out.
Cagliari have only won once at home this season and the odds are on Inter extending a winning run that has seen them surge to the top despite strong opposition from Roma and Juventus.
Roma have talismanic skipper Francesco Totti back but could be faced with a tougher task at Torino, who have only been defeated once at home this year.
Third-placed Juventus, three behind Roma, visit 12th-placed Lazio with the hosts' spirits low after being dumped out of the Champions league by Real Madrid.
But Juve have only won once away from home this season and are without winger Mauro Camoranesi, out with a thigh strain until next month.
However, they are expected to field in-form skipper Alessandro Del Piero from the start.
Udinese, one point behind Juve, travel to 11th-placed Catania while fifth-placed Fiorentina, four behind Udinese, visit Sampdoria, four places and four points below them.
